As part of its new Center for Stem Cell Bioinformatics, the Harvard Stem Cell Institute (HSCI) has partnered with the Harvard School of Public Health Bioinformatics Core (HBC) to improve Bioinformatics assessment of stem cell regulation and function. Integral to the HSCI, our multi-disciplinary team works with HSCI researchers across the Harvard, MIT and Broad biomedical community, providing a comprehensive portfolio of infrastructure, data analysis, training and development to HSCI researchers. As we expand the team we seek an experienced computational biologist to become an integral component of the partnership and provide dedicated bioinformatics expertise to the Massachusetts General Hospital Center for Regenerative Medicine (CRM).
This is a unique opportunity to participate in world-class stem cell research that aims to make an impact on human health. You will be working directly with researchers on projects ranging from understanding hematopoietic stem cell biology, to muscle regeneration or the role of pluripotency genes in stem-cell self renewal or cancer. You will act as the liaison between HBC and CRM to ensure developed solutions can be standardized and made available to the broader scientific community.
You have a background in biomedical or quantitative science and a strong interest in working with researchers in stem cell biology and regenerative medicine. You thrive on scientific challenges, enjoy collaborating with an interdisciplinary team and excel at communicating and coordinating between programmers and wet-lab scientists alike. Learning and applying new methods is natural for you, and you are motivated to continuously expand your skills. You have a good handle on your data and project management skills. Working on different projects and deadlines, frequently in collaboration with other Cores and research groups, doesn’t intimidate you. You enjoy teaching and organizing workshops to train other researchers in newly developed methods and workflows.
You will support researchers at CRM with their data management, quality control, analysis of data and presentation of results. Projects are usually a mix of short-term support tasks and long-term collaborations; most support tasks and methods should eventually transition into standardized workflows. You will need broad experience in several bioinformatics domains such as microarray analysis (mRNA, miRNA), sequencing (RNA-seq, ChIP-seq, Exome-seq) or functional analysis. You will be the initial point of contact for CRM researchers, work with the HBC director to prioritize projects and expand the HSCI Core Bioinformatics Program.
- PhD in a biomedical or quantitative science (or equivalent experience), 2+ years of work experience
- Expertise in at least one listed bioinformatics domain
- Evidence of working directly with wet laboratories to perform analyses
- Proven ability to interpret and analyze large data sets and present results synthetically
- Working knowledge of biology, genetics and cell biology
- Excellent written English and a familiarity with presenting biological results
- Strong interpersonal skills
- Computational experience
- Scripting abilities (Perl, Python)
- Experience with R/BioC, GenePattern, Galaxy or similar environments
- Competency in statistics
- Demonstrated experience in teaching and outreach
How to apply
Send us an email with your CV, cover letter and any questions you might have.